• Corpus ID: 69030964

Procalcitonin : biochemistry and clinical diagnosis

@inproceedings{Meisner2010ProcalcitoninB,
  title={Procalcitonin : biochemistry and clinical diagnosis},
  author={Michael Meisner},
  year={2010}
}
At present, Procalcitonin (PCT) is one of the best parameters for the early detection and monitoring of severe bacterial infections and sepsis. More than 1,500 scientific publications on PCT account for the most significant areas of application of this marker. PCT helps identify or rule out severe bacterial infections. It provides a relatively high degree of certainty in the differential diagnosis of “sepsis”, “severe sepsis” or “septic shock”. In conjunction with other clinical data, PCT… 
นิพนธ์ต้นฉบับ Procalcitonin and Interleukin-6 in pediatric patients admitted with suspected sepsis at Tertiary Care Hospital
Background Bacterial sepsis remains one of the leading causes of mortality and morbidity among children. Early identification of individuals at risk of developing life-threatening sepsis could enable
Diagnostic and Prognostic Value of Procalcitonin in Tuberculosis Patients
TLDR
The results indicated that PCT levels served as a useful marker of infection in PTB patients at diagnosis, thus indicating that prohormone level was > 2ng/ml in fifteen and > 10 ng/ml on average in the rest of the PTB-0 subjects.
Correlation Between Time to Positivity Blood Culture and Procalcitonin on Bacteremia Patient
TLDR
Significantly higher levels of procalcitonin in cases of bacteremia are more likely to be caused by Gram-negative bacteria than Gram-positive bacteria.
Can procalcitonin levels indicate the need for adjunctive therapies in sepsis?
TLDR
The purpose of this review is to give an overview on the pathophysiology of sepsis as well as the role and interpretation of biomarkers and their potential use in assisting adjunctive therapies in sepsi in the future.
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Assessing the clinical impact of severe sepsis and the diagnostic properties of clinical and biological markers in patients with a suspected or established serious infection concluded that increased C-reactive protein, white blood cell count, respiratory rate and a decreased hemoglobin level contributed independently to an accurate selection of patients for antibiotic therapy.
The clinical significance of sCD14-ST for blood biomarker in neonatal hematosepsis
Abstract Hematosepsis is a systemic inflammatory response syndrome (SIRS) with suspected or confirmed infection, which is the most common infectious disease in clinical neonatal intensive care unit.
Higher cut-off serum procalcitonin level for sepsis diagnosis in metastatic solid tumor patients
TLDR
The results show that metastatic tumor affects the patients’ procalcitonin level, even in the absence of sepsis, and the cut-off point for sepsi in the meta-static solid tumor was higher compared to the standard value.
Monitoring both procalcitonin and C-reactive protein in the early period after tetralogy of Fallot correction in children promotes rational antibiotic use.
TLDR
Monitoring both CRP and PCT in the early postoperative period may guide antibiotic therapy, thus reducing unnecessary treatment, additional toxicity, and adverse drug interactions without increasing treatment failure.
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TLDR
Elevated value of PCT at admission has moderate accuracy to identify poor outcome in ED septic patients in daily practice and similar results were obtained when considering the combined outcome death and/or admission in ICU.
Vpliv vrste povzročitelja na porast koncentracije prokalcitonina pri bolnikih s sepso Infectious agent's influence on serum procalcitonin concentration in patients with sepsis
TLDR
Causative agent has a significant effect on serum PCT concentration in patients with sepsis, and amongst Gram-positive pathogens, S. aureus caused greater rise in PCT than other Gram- positive bacteria put together.
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