Procaine is a specific DNA methylation inhibitor with anti-tumor effect for human gastric cancer.

@article{Li2018ProcaineIA,
  title={Procaine is a specific DNA methylation inhibitor with anti-tumor effect for human gastric cancer.},
  author={Yong-Chao Li and Yun Wang and Dan-Dan Li and Ying Zhang and Tian-Cheng Zhao and Chang-feng Li},
  journal={Journal of cellular biochemistry},
  year={2018},
  volume={119 2},
  pages={
          2440-2449
        }
}
DNA hypermethylation and the silencing of tumor suppressor genes caused by DNA hypermethylation is considered as a molecular hallmark of many kinds of cancers. Procaine, a local anesthetic, has been shown as a potential DNA methylation inhibitor in some types of cancers. However, the influence of procaine on DNA methylation regulation as well as the… CONTINUE READING