Probucol prevents early coronary heart disease and death in the high-density lipoprotein receptor SR-BI/apolipoprotein E double knockout mouse.

Abstract

Mice with homozygous null mutations in the high-density lipoprotein receptor SR-BI (scavenger receptor class B, type I) and apolipoprotein E genes fed a low-fat diet exhibit a constellation of pathologies shared with human atherosclerotic coronary heart disease (CHD): hypercholesterolemia, occlusive coronary atherosclerosis, myocardial infarctions, cardiac… (More)

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@article{Braun2003ProbucolPE, title={Probucol prevents early coronary heart disease and death in the high-density lipoprotein receptor SR-BI/apolipoprotein E double knockout mouse.}, author={Anne J. Braun and Songwen Zhang and Helena E. Miettinen and Shamsah Ebrahim and Teresa M. Holm and Eliza Vasile and Mark J. Post and Danita M. Yoerger and Michael H Picard and Joshua L. Krieger and Nancy Catherine Andrews and Michael Simons and Monty Krieger}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2003}, volume={100 12}, pages={7283-8} }