Problems of Cold Agglutinins in Cardiac Surgery: How to Manage Cardiopulmonary Bypass and Myocardial Protection

  title={Problems of Cold Agglutinins in Cardiac Surgery: How to Manage Cardiopulmonary Bypass and Myocardial Protection},
  author={K. Alizadeh and M. Tabari and Behrooz Mottahedi and Delaram Sayadpour},
  journal={journal of cardio-thoracic medicine},
  • K. Alizadeh, M. Tabari, +1 author Delaram Sayadpour
  • Published 2014
  • Medicine
  • journal of cardio-thoracic medicine
  • Article type: Case Report Cold agglutinins are of unique relevance in cardiac surgery because of the use of hypothermic cardiopulmonary bypass (CPB). Cold autoimmune diseases are defined by the presence of abnormal circulating proteins (usually IgM or IgA antibodies) that agglutinate in response to a decrease in body temperature. These disorders include cryoglobulinemia and cold hemagglutinin disease. Immunoglobulin M autoantibodies to red blood cells, which activate at varying levels of… CONTINUE READING
    2 Citations


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