• Corpus ID: 8085495

Problems in the Laboratory Diagnosisof Alcaptonuria

@inproceedings{Frohlich2004ProblemsIT,
  title={Problems in the Laboratory Diagnosisof Alcaptonuria},
  author={Jiri Frohlich and George E. Price and Donald J. Campbell},
  year={2004}
}
Two patients with urinary findings suggestive of alcaptonuria were observed. One was a two-year-old girl of Turkish descent, presenting with dark-stained diapers, black ear wax, and no other stated problem. The second was a 61-year-old North American Indian woman with long-standing rheumatoid arthritis, bluish sclerae, chronic renal failure, and dark urine. Diagnosis of alcaptonuria was confirmed in the first case by paper chromatographic identification of homogentisic acid in urine and ear wax… 

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