Probleme der Lateralität und neurophysiologische Befunde bei Schizophrenien

  title={Probleme der Lateralit{\"a}t und neurophysiologische Befunde bei Schizophrenien},
  author={W. G{\"u}nther and R. Steinberg and David Breitling and P. Davous and J. L. Godet and E. Moser and R. Petsch and H. Heller and L. Raith and P. Streck},
In eine Serie von psychometrischen und neurophysiologischen Studien versuchten wir, mogliche zentrale Korrelate gestorter motorischer Funktion bei Untergruppen schizophrener Patienten aufzufinden. Besonderen Wert legten wir hierbei auf die Erfassung der Psychopathologie in Hinblick auf eine „positivnegativ Dimension“(z. B. Bleuler 1930; Schneider 1957; Huber et al. 1979; Andreasen 1982). In dem hier vorgelegten Uberblick uber unsere „Neuroimaging“-Studien haben wir als hypothesenbildenden… Expand
2 Citations
Psychomotor disturbances in psychiatric patients as a possible basis for new attempts at differential diagnosis and therapy
Results suggest pathological brain organization connected to an impaired motor performance (evident peripherally as PMS) in schizophrenic and endogenous depressed patients and provide further neurophysiological basis for the use of motor training programs in the additional therapy of psychiatric patients. Expand
Psychomotor disturbances in psychiatric patients as a possible basis for new attempts at differential diagnosis and therapy
The PMS showed a clear improvement with the amelioration of the depressive symptoms in endogenous depressed patients towards the end of the hospital treatment period and disappeared entirely in patients in a symptom free interval, suggestive of a possible role for the PMS as a state marker for endogenous depression, in contrast to the persistence of thePMS in schizophrenics. Expand


Psychomotorische Störungen bei psychiatrischen Patienten als mögliche Grandlage neuer Ansätze in Differentialdiagnose und Therapie
The movement disturbances in psychotic patients, which have been measured by a broader standardized battery, could be the starting point in the development of specific psychomotor training programmes, which could improve the efficiency of conventional gymnastic and ergotherapeutic treatment methods. Expand
Bilateral brain dysfunction during motor activation in type II schizophrenia measured by EEG mapping
Evidence of bilateral hemispheric dysfunction in type II patients reported by other authors using EEG, evoked potentials, regional cerebral blood flow (rCBF) and magnetic resonance imaging (MRI) methods suggests that marked bilateral brain dysfunction may be correlated in schizophrenia with a clinical syndrome corresponding rather to the "negative pole" of the positive-negative dimension. Expand
Predominant sensorimotor area left hemisphere dysfunction in schizophrenia measured by brain electrical activity mapping
Using a newly developed system of brain electrical activity mapping, right-handed, schizophrenic subjects who had been treated with neuroleptics are studied and a widespread left hemisphere dysfunction during multisensorimotor activation is found, with a predominance over the primary sensory and motor cortical areas. Expand
EEG Mapping of left hemisphere dysfunction during motor performance in schizophrenia
The results in these patients suggest that these are not merely vigilance, attention, or motivation dysfunctions, but rather specific cortical correlates of impaired motor performance, and support the findings obtained during multisensory motor coordination in schizophrenia. Expand
Preliminary experiences and results with the Munich version of the Andreasen Scale. Assessment of productive and negative symptoms in chronic schizophrenic patients.
The results suggest that the SANS is a reliable instrument for measuring negative symptoms; however, the symptom complexes are affected by age, duration of illness and hospitalization, thus making a clear distinction between negative symptoms per se and the effects of hospitalization questionable. Expand
Brain function in psychiatric disorders. III. Regional cerebral blood flow in unmedicated schizophrenics.
Comparison with an earlier sample of medicated schizophrenics suggested that neuroleptics restore symmetry of resting flows before they produce symptomatic relief, supporting the hypothesis of left hemispheric overactivation. Expand
Negative symptoms in schizophrenia. Definition and reliability.
  • N. Andreasen
  • Psychology, Medicine
  • Archives of general psychiatry
  • 1982
The developed Scale for the Assessment of Negative Symptoms has excellent interrater reliability and the five symptom complexes defined by the scale have good internal consistency, which indicates that the conceptual organization of the scale is also cohesive. Expand
Dissociation of smooth-pursuit and saccadic eye tracking in remitted schizophrenics. An ocular reaction time task that schizophrenic perform well.
Twenty-four schizophrenic outpatients in remission were compared with 21 medical outpatient controls on tasks designed to evaluate smooth pursuit of different frequency sinusoidal targets, saccadicExpand
Pathological cerebral blood flow during motor function in schizophrenic and endogenous depressed patients
The results suggest a diffuse disorganization and lack of laterality of motor functional systems in schizophrenic patients, and the change from hyperactivity to hyporeactivity might indicate cerebral functional correlates of thechange from Type I to Type II symptomatology in schizophrenics, which could possible prove to be of clinical importance. Expand
Alterations in cerebral laterality during acute psychotic illness.
  • B. Wexler
  • Psychology, Medicine
  • The British journal of psychiatry : the journal of mental science
  • 1986
A new dichotic listening test was used to monitor changes in perceptual asymmetry in patients recovering from acute psychotic episodes, and contrary to expectation, PA on the word test decreased with recovery, while asymmetry on the tone and dot tests did not change. Expand