Problem in prolonged levodopa administration of Parkinson disease patients--from the standpoint of the autonomic nervous function.

We studied 50 patients with Parkinson's disease to determine any relation of epidemiologic factors (such as the duration of illness), the duration of levodopa therapy, the total amount of administered levodopa to degree of autonomic dysfunction. Autonomic dysfunction was evaluated using the composite autonomic scoring scale (CASS). The CASS scores were… CONTINUE READING