Probiotics to prevent or treat excessive infant crying: systematic review and meta-analysis.

  title={Probiotics to prevent or treat excessive infant crying: systematic review and meta-analysis.},
  author={Valerie Sung and Sarsha Collett and Tanyth E de Gooyer and Harriet Hiscock and M. L.-K. Tang and Melissa Wake},
  journal={JAMA pediatrics},
  volume={167 12},
IMPORTANCE Excessive infant crying is common, distressing, but without proven effective prevention or management options. Probiotics may be a promising solution. OBJECTIVE To examine whether probiotics are effective in the prevention/management of crying ("colic") in infants 3 months or younger. DATA SOURCES A systematic search of MEDLINE, EMBASE, and the Cochrane Library, supplemented by the metaRegister of Controlled Trials. STUDY SELECTION Studies that randomized infants 3 months or younger… CONTINUE READING
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