Probiotics Reduce Gut Microbial Translocation and Improve Adult Atopic Dermatitis

@article{Iemoli2012ProbioticsRG,
  title={Probiotics Reduce Gut Microbial Translocation and Improve Adult Atopic Dermatitis},
  author={Enrico Iemoli and Daria Trabattoni and Serena Parisotto and Linda Borgonovo and Marco Toscano and Giuliano Rizzardini and Mario Clerici and Elena Ricci and A. Fusi and Elena De Vecchi and Stefania Piconi and Lorenzo Drago},
  journal={Journal of Clinical Gastroenterology},
  year={2012},
  volume={46},
  pages={S33–S40}
}
Background: It has been suggested that probiotics modulate atopic dermatitis (AD) progression, but no data are actually available on their mechanisms of action and on their ability to act as immunomodulators in this pathology. Objective: The aim of this randomized double-blinded active treatment versus placebo study was to evaluate clinical efficacy of an intake of a combination of 2 probiotics (Lactobacillus salivarius LS01 and Bifidobacterium breve BR03) for the treatment of adult AD patients… Expand
View on Wolters Kluwer
sbne.org.br
33 Citations
Background Citations
1

Paper Mentions

Interventional Clinical Trial
NEOBIFI: Clinical Trial for the Prevention and/or Reduction of the Incidence of Colics in Infants
Infant colics represent a clinical condition in childhood, characterized by an uncontrollable crying that occurs without any apparent organic cause.1 They can be associated with face… Expand
ConditionsBifidobacterium Breve, Colic, Infantile, Gut Microbiome, (+1 more)
InterventionDrug
Azienda Ospedaliero Universitaria Maggiore della Carita
October 2013 - July 2017
Blog Post
Colostrum Meets the Microbiome A Tried and True Remedy for Gut Health Takes Centre Stage
Nutri-Link Ltd - Clinical Education
24 April 2014

33 Citations

Citation Type

Citation Type

Beneficial Effect of Lactobacillus plantarum IS-10506 Supplementation in Adults with Atopic Dermatitis: A Randomized Controlled Trial.
TLDR
The administration of Lactobacillus plantarum IS-10506 is effective for alleviating AD symptoms in adults owing to its immunomodulatory effects. Expand
Effects of probiotics for the treatment of atopic dermatitis: a meta-analysis of randomized controlled trials.
TLDR
It is suggested that probiotics could be an option for the treatment of AD, especially for moderate to severe AD in children and adults, however, no evidence was found supporting the beneficial role of probiotics in infants. Expand
Effect of Oral Administration of a Mixture of Probiotic Strains on SCORAD Index and Use of Topical Steroids in Young Patients With Moderate Atopic Dermatitis: A Randomized Clinical Trial
TLDR
The mixture of probiotics was effective in reducing SCORAD index and reducing the use of topical steroids in patients with moderate atopic dermatitis in a 12-week randomized, double-blind, placebo-controlled intervention trial. Expand
Probiotics and diseases of altered IgE regulation: A short review
TLDR
There is currently little reliable scientific data that supports the theory that there exists a cause–effect relationship between taking probiotics and alleviation of allergic disease, and these findings are too variable to allow substantial conclusions as to the efficacy and effectiveness of probiotic use in these disease states. Expand
Probiotics with ameliorating effects on the severity of skin inflammation in psoriasis: Evidence from experimental and clinical studies
TLDR
This review considered the impact of gastrointestinal microbiota on the psoriasis pathogenesis, and through literature survey, attempted to explore probiotic species utilized for Psoriasis treatment. Expand
Probiotics and Periodontal Diseases
TLDR
A growing number of studies support probiotic therapy to prevent or treat gingivitis and periodontitis and oral administration of probiotics is an effective adjunct in reducing pathogenic bacteria and improving clinical signs of disease. Expand
Multispecies probiotic protects gut barrier function in experimental models.
TLDR
LT significantly prevented the epithelial disruption induced by intracolonic infusion of fecal supernatant from IBS patients and increased the expression of occludin in vitro and in vivo, as assessed by immnunoblotting. Expand
Effects of probiotics and synbiotic supplementation on antioxidant status: A meta-analysis of randomized clinical trials.
TLDR
Probiotics and synbiotics supplementation improve GSH as a biomarkers of antioxidant status in the body, however, additional studies needed for concluding about TAC and SOD activity. Expand
Probiotic supplements might not be universally-effective and safe: A review.
TLDR
The safety perspectives of probiotics and their therapeutic interventions in certain at-risk population groups are discussed and the embodied arguments and hypotheses certainly will shed light on the fact why probiotic usage should be treated with caution. Expand
Lactobacillus plantarum NCIMB8826 ameliorates inflammation of colon and skin in human APOC1 transgenic mice.
TLDR
Modulation of intestinal immune homeostasis contributes to the suppression of atopic dermatitis in hyperlipidemic human APOC1(+/+) mice. Expand
...
1
2
3
4
...

References

SHOWING 1-10 OF 55 REFERENCES
Therapeutic Effects of Probiotics in Patients with Atopic Dermatitis
TLDR
The results suggest that the treatment with the mixture of four probiotic strains is beneficial for the management of the adolescent and adult AD patients, as well as for the childhood AD patients. Expand
Clinical Effects of Probiotic Bifidobacterium breve Supplementation in Adult Patients with Atopic Dermatitis
TLDR
The results suggest that B. breve may be beneficial for the treatment of atopic dermatitis, however, since the severity of disease symptoms in the placebo group at the beginning of the study was milder than those in the probiotic group, further study is needed to determine the clinical value of B. Breve. Expand
Effects of Lactobacillus Salivarius LS01 (DSM 22775) Treatment on Adult Atopic Dermatitis: A Randomized Placebo-Controlled Study
TLDR
In this study, the administration of L. salivarius LS01 was well tolerated and was associated with a significant improvement of clinical manifestation and QoL and could be considered as an important adjunctive therapy in the treatment of adult AD. Expand
Probiotics for the Treatment or Prevention of Atopic Dermatitis
TLDR
Probiotics, especially L. rhamnosus GG, seem to be effective for the prevention of AD, and were found to reduce the severity of AD in approximately half of the RCTs evaluated, although they were not found to change significantly most of the inflammatory markers measured in the majority of theRCTs evaluation. Expand
Probiotics in the atopic march: highlights and new insights.
  • M. M. del Giudice, A. Rocco, C. Capristo
  • Medicine
  • Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
  • 2006
TLDR
It is hypothesize that it may be possible, in the future, to use probiotics in primary prevention of asthma. Expand
Effect of probiotics on gastrointestinal symptoms and small intestinal permeability in children with atopic dermatitis.
TLDR
It is suggested that probiotic supplementation may stabilize the intestinal barrier function and decrease gastrointestinal symptoms in children with atopic dermatitis. Expand
Probiotics in Allergy Management
  • J. Vanderhoof
  • Medicine
  • Journal of pediatric gastroenterology and nutrition
  • 2008
TLDR
In conclusion, probiotics are effective in the treatment and/or prevention of a number of conditions, including diarrhoea, irritable bowel syndrome and atopic dermatitis, and the product used should be selected based on the particular indication. Expand
Successful management of mild atopic dermatitis in adults with probiotics and emollients
TLDR
It is demonstrated that regular use of probiotics with antioxidative properties coupled with the use of lipid-containing emollients considerably decreases inflammation and concomitant oxidative stress in adult patients with mild-to-moderate atopic dermatitis. Expand
The Rationale and Clinical Effectiveness of Probiotics in Irritable Bowel Syndrome
TLDR
The rationale for targeting the intestinal microbiota in patient with IBS is discussed and an overview and a critical evaluation of the currently available clinical data on the use of probiotics in the treatment of patientswith IBS are provided. Expand
[Effects of administration of bifidobacteria on fecal microflora and clinical symptoms in infants with atopic dermatitis].
TLDR
The tendency of allergic symptom improvement in the bifidobacteria-administered group was remarkable compared with the control group; however, there was no correlation between changes in fecal microflora and allergic symptoms. Expand
...
1
2
3
4
5
...