Probiotic supplementation and trimethylamine-N-oxide production following a high-fat diet.

@article{Boutagy2015ProbioticSA,
  title={Probiotic supplementation and trimethylamine-N-oxide production following a high-fat diet.},
  author={Nabil Boutagy and Andrew P Neilson and Kristin L Osterberg and Andrew T Smithson and Tessa R Englund and Brenda M Davy and Matthew W. Hulver and Kevin P. Davy},
  journal={Obesity},
  year={2015},
  volume={23 12},
  pages={2357-63}
}
OBJECTIVE The objective of this study was to test the hypothesis that the multi-strain probiotic VSL#3 would attenuate the increase in fasting plasma concentrations of trimethylamine-N-oxide (TMAO) following a high-fat diet. METHODS Nineteen healthy, non-obese males (18-30 years) participated in the present study. Following a 2-week eucaloric control diet, subjects were randomized to either VSL#3 (900 billion live bacteria) or placebo (cornstarch) during the consumption of a hypercaloric (+1… CONTINUE READING
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