Probiotic Therapy: Immunomodulating Approach Toward Urinary Tract Infection

@article{Amdekar2011ProbioticTI,
  title={Probiotic Therapy: Immunomodulating Approach Toward Urinary Tract Infection},
  author={Sarika Amdekar and Vinod Kumar Singh and Desh D. Singh},
  journal={Current Microbiology},
  year={2011},
  volume={63},
  pages={484-490}
}
Urinary tract infection (UTI) is an extremely common health problem, with an unpredictable history. Members of enterobacteriaceae family such as Escherichia coli, which are normal inhabitants of human intestines, account for the majority of these uncomplicated infections. Rarely, UTI can result from virus or fungus. There is a close correlation between loss of the normal genital microbiota, particularly Lactobacillus species, and an increased incidence of genital and bladder infections… Expand
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TLDR
Probiotics can be used as a natural and efficient alternative to antibiotics in UTI prophylaxis and treatment in children. Expand
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There must be active research in phyto-based therapies of UTIs, such as Ayurvedic Biology, as the role of medicinal plant-based nanotechnology approaches has shown promising results. Expand
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TLDR
Evidence for the nonantibiotic measures is hampered by considerable heterogeneity, and further placebo-controlled randomized trials of these agents are needed, so firm recommendations for their use can be made. Expand
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TLDR
The importance of the use of urogenital probiotics is that it is a natural approach that replenishes the depleted normal flora to create a better environment to fight off uropathogens. Expand
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TLDR
It was found that microbial infections including Escherichia coli, Enterococcus faecalis and Klebsiella species are the major causes of UTI with different signs and symptoms including painful urination or dysuria, hematuria, urinary urgency, burning micturition, frequent urination, nausea, and vomiting. Expand
Proteomic analysis of uropathogenic Escherichia coli
  • P. Cash
  • Biology, Medicine
  • Expert review of proteomics
  • 2014
TLDR
Proteomic analyses have complemented the genomic data and have documented differential patterns of protein synthesis for bacteria growing ex vivo in human urine or recovered directly from the urinary tracts of infected mice, providing valuable insights into the molecular basis of UPEC pathogenesis. Expand
Deep insights into urinary tract infections and effective natural remedies
Background Urinary tract infection (UTI) is a common occurrence in females, during pregnancy, and in peri- and postmenopausal women. UTIs are associated with significant morbidity and mortality, and… Expand
Detection of virulence markers of uropathogenic escherichia coli from urinary tract infections and its antimicrobial susceptibility pattern
TLDR
The knowledge of virulence factors of E. coli and their antibiotic susceptibility pattern will help in better understanding of the organism and in the treatment of UTI. Expand
Epidemiology and Virulence of Klebsiella pneumoniae.
TLDR
The development of both in vitro and in vivo models of infection will lead to further elucidation of the molecular pathogenesis of K. pneumoniae, and the role of host factors as well as bacterial traits are crucial in determining the outcome of infections. Expand
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