Probiotic Lactobacillus strains: in vitro and in vivo studies

  title={Probiotic Lactobacillus strains: in vitro and in vivo studies},
  author={Bożena Cukrowska and Ilona Motyl and Hana Koz{\'a}kov{\'a} and Martin Schwarzer and Roman K. G{\'o}recki and Elżbieta Klewicka and Katarzyna Śliżewska and Zdzisława Libudzisz},
  journal={Folia Microbiologica},
Three Lactobacillus strains (LOCK 0900, LOCK 0908, LOCK 0919) out of twenty-four isolates were selected according to their antagonistic activity against pathogenic bacteria, resistance to low pH and milieu of bile salts. Intragastric administration of a mixture of these strains to Balb/c mice affected cytokine TH1-TH2 balance toward nonallergic TH1 response. Spleen cells, isolated from lactobacilli-treated mice and re-stimulated in vitro with the mixture of heat-inactivated tested strains… CONTINUE READING