Probing water micro-solvation in proteins by water catalysed proton-transfer tautomerism.

Abstract

Scientists have made tremendous efforts to gain understanding of the water molecules in proteins via indirect measurements such as molecular dynamic simulation and/or probing the polarity of the local environment. Here we present a tryptophan analogue that exhibits remarkable water catalysed proton-transfer properties. The resulting multiple emissions… (More)
DOI: 10.1038/ncomms3611

Topics

5 Figures and Tables