Probing tissue multifractality using wavelet based multifractal detrended fluctuation analysis: Applications in precancer detection

  title={Probing tissue multifractality using wavelet based multifractal detrended fluctuation analysis: Applications in precancer detection},
  author={Jalpa Soni and Gregor P. Jose and Sayantani Ghosh and Asima Pradhan and Tapas Kumar Sengupta and Prasanta K. Panigrahi and Nirmalya Ghosh},
  journal={2011 4th International Conference on Biomedical Engineering and Informatics (BMEI)},
  • J. Soni, Gregor P. Jose, N. Ghosh
  • Published 13 July 2011
  • Physics
  • 2011 4th International Conference on Biomedical Engineering and Informatics (BMEI)
The refractive index fluctuations in the connective tissue layer (stroma) of human cervical tissues having different grades of precancers (dysplasia) was quantified using a wavelet-based multifractal detrended fluctuation analysis model. The results show clear signature of multi-scale self-similarity in the index fluctuations of the tissues. Importantly, the refractive index fluctuations were found to be more anti-correlated at higher grades of precancers. Moreover, the strength of… 

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