Probing the unique dehydration-induced structural modifications in cancer cell DNA using surface enhanced Raman spectroscopy.

Abstract

Conformation-induced formation of a series of unique Raman marker bands in cancer cell DNA, upon dehydration, have been probed for the first time with the use of surface enhanced Raman spectroscopy (SERS). These bands are capable of distinguishing cancer cell DNA from healthy cell DNA. For this simple and label-free DNA detection approach, we used… (More)
DOI: 10.1021/ja400187b

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