Probing the role of sequence in the assembly of three-dimensional DNA crystals.

@article{Saoji2015ProbingTR,
  title={Probing the role of sequence in the assembly of three-dimensional DNA crystals.},
  author={Maithili Saoji and Daoning Zhang and Paul J Paukstelis},
  journal={Biopolymers},
  year={2015},
  volume={103 11},
  pages={618-26}
}
DNA is a widely used biopolymer for the construction of nanometer-scale objects due to its programmability and structural predictability. One long-standing goal of the DNA nanotechnology field has been the construction of three-dimensional DNA crystals. We previously determined the X-ray crystal structure of a DNA 13-mer that forms a continuously hydrogen bonded three-dimensional lattice through Watson-Crick and non-canonical base pairs. Our current study sets out to understand how the sequence… CONTINUE READING
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