Probing the relation between force--lifetime--and chemistry in single molecular bonds.

  • Evan A. Evans
  • Published 2001 in
    Annual review of biophysics and biomolecular…


On laboratory time scales, the energy landscape of a weak bond along a dissociation pathway is fully explored through Brownian-thermal excitations, and energy barriers become encoded in a dissociation time that varies with applied force. Probed with ramps of force over an enormous range of rates (force/time), this kinetic profile is transformed into a… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.