Probing the pharmacokinetics of cucurbit[7, 8 and 10]uril: and a dinuclear ruthenium antimicrobial complex encapsulated in cucurbit[10]uril.

@article{Li2017ProbingTP,
  title={Probing the pharmacokinetics of cucurbit[7, 8 and 10]uril: and a dinuclear ruthenium antimicrobial complex encapsulated in cucurbit[10]uril.},
  author={Fangfei Li and Anil Kumar Gorle and Marie Ranson and Kara L Vine and Robert T Kinobe and Marshall L Feterl and Jeffrey M. Warner and F Richard Keene and J. Grant Collins and Anthony I Day},
  journal={Organic & biomolecular chemistry},
  year={2017},
  volume={15 19},
  pages={4172-4179}
}
The relatively non-toxic family of cucurbit[n]uril, Q[n], have shown considerable potential in vitro as drug delivery agents, with only a few examples of pharmacokinetic (PK) studies for drug⊂Q[n]. Drug-free Q[n] PK studies are the next step in determining the pharmacological applicability in their drug delivery potential. The results for the first PK and… CONTINUE READING