Probing the network structure of health deficits in human aging

  title={Probing the network structure of health deficits in human aging},
  author={Spencer G. Farrell and Arnold Mitnitski and Olga Theou and Kenneth Rockwood and Andrew D. Rutenberg},
Human aging leads to the stochastic accumulation of damage. We model an aging population using a stochastic network model. Individuals are modeled as a network of interacting nodes, representing health attributes. Nodes in the network stochastically damage and repair, with rates dependent on the state of their neighbors. Damaged nodes represent health deficits. The Frailty Index (FI) assesses age-related damage as the proportion of health deficits an individual has accumulated, from a selection… 
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