Probing the impact of axial diffusion on nitric oxide exchange dynamics with heliox.

@article{Shin2004ProbingTI,
  title={Probing the impact of axial diffusion on nitric oxide exchange dynamics with heliox.},
  author={H W Shin and Peter Condorelli and Christine M. Rose-Gottron and Dan M. Cooper and Steven George},
  journal={Journal of applied physiology},
  year={2004},
  volume={97 3},
  pages={874-82}
}
Exhaled nitric oxide (NO) is a potential noninvasive index of lung inflammation and is thought to arise from the alveolar and airway regions of the lungs. A two-compartment model has been used to describe NO exchange; however, the model neglects axial diffusion of NO in the gas phase, and recent theoretical studies suggest that this may introduce significant error. We used heliox (80% helium, 20% oxygen) as the insufflating gas to probe the impact of axial diffusion (molecular diffusivity of NO… CONTINUE READING