Probing the binding of two fluoroquinolones to lysozyme: a combined spectroscopic and docking study.

@article{Qin2012ProbingTB,
  title={Probing the binding of two fluoroquinolones to lysozyme: a combined spectroscopic and docking study.},
  author={Pengfei Qin and Baoling Su and Rutao Liu},
  journal={Molecular bioSystems},
  year={2012},
  volume={8 4},
  pages={1222-9}
}
Ciprofloxacin (CPFX) and enrofloxacin (ENFX) are two of the most widely used fluoroquinolones (FQs) in human and veterinary medicines. Their occurrence in the environment has received much attention because of the potential adverse effects on humans and ecosystem functions. In this paper, we investigated the interaction mechanism between the two FQs and lysozyme by the spectroscopic and molecular docking methods. As shown by the fluorescence spectroscopy, additions of CPFX or ENFX effectively… CONTINUE READING

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