Probing the Single Key Amino Acid Responsible for the Novel Catalytic Function of ent-Kaurene Oxidase Supported by NADPH-Cytochrome P450 Reductases in Tripterygium wilfordii

@inproceedings{Su2017ProbingTS,
  title={Probing the Single Key Amino Acid Responsible for the Novel Catalytic Function of ent-Kaurene Oxidase Supported by NADPH-Cytochrome P450 Reductases in Tripterygium wilfordii},
  author={Ping Su and Hongyu Guan and Yifeng Zhang and Xing Wang and Linhui Gao and Yujun Zhao and Tianyuan Hu and Jiawei Zhou and Baowei Ma and Lichan Tu and Yuru Tong and Lu-qi Huang and Wei Gao},
  booktitle={Front. Plant Sci.},
  year={2017}
}
Tripterygium wilfordii produces not only ent-kaurene, which is an intermediate of gibberellin (GA) biosynthesis in flowering plants, but also 16α-hydroxy-ent-kaurane, whose physiological role has not been characterized. The two compounds are biosynthesized from the universal diterpenoid precursor (E,E,E)-geranylgeranyl diphosphate (GGPP) by diterpene synthases, which have been discovered and functionally characterized in T. wilfordii. Here, we described the functional characterization of four… CONTINUE READING
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