Probing the Limits to Positional Information

Abstract

The reproducibility and precision of biological patterning is limited by the accuracy with which concentration profiles of morphogen molecules can be established and read out by their targets. We consider four measures of precision for the Bicoid morphogen in the Drosophila embryo: the concentration differences that distinguish neighboring cells, the limits… (More)
DOI: 10.1016/j.cell.2007.05.025

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