Probing the Borrelia burgdorferi surface lipoprotein secretion pathway using a conditionally folding protein domain.

@article{Chen2011ProbingTB,
  title={Probing the Borrelia burgdorferi surface lipoprotein secretion pathway using a conditionally folding protein domain.},
  author={Shiyong Chen and Wolfram R. Z{\"u}ckert},
  journal={Journal of bacteriology},
  year={2011},
  volume={193 23},
  pages={6724-32}
}
Surface lipoproteins of Borrelia spirochetes are important virulence determinants in the transmission and pathogenesis of Lyme disease and relapsing fever. To further define the conformational secretion requirements and to identify potential lipoprotein translocation intermediates associated with the bacterial outer membrane (OM), we generated constructs in which Borrelia burgdorferi outer surface lipoprotein A (OspA) was fused to calmodulin (CaM), a conserved eukaryotic protein undergoing… CONTINUE READING
5 Citations
63 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 63 references

Structure, function and biogenesis of the Borrelia cell envelope, p. 139–166

  • S. Bergström, W. R. Zückert
  • 2010
Highly Influential
4 Excerpts

Crystal VOL

  • C. L. Lawson, B. H. Yung, A. G. Barbour, W. R. Zückert
  • J. Bacteriol
  • 2006
Highly Influential
9 Excerpts

Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi

  • Fraser, M C.
  • Nature
  • 1997
Highly Influential
2 Excerpts

Similar Papers

Loading similar papers…