• Corpus ID: 231802288

Probing single-molecule conformational heterogeneity at room temperature via hyperspectral tip-enhanced Raman imaging

  title={Probing single-molecule conformational heterogeneity at room temperature via hyperspectral tip-enhanced Raman imaging},
  author={Mingu Kang and Hyunwoo Kim and Elham Oleiki and Yeonjeong Koo and Hyeongwoo Lee and T. J. Eom and Geunsik Lee and Yung Doug Suh and Kyoung-Duck Park},
Cryogenic tip-enhanced Raman spectroscopy (TERS) studies have revealed singlemolecule dynamics; however, understanding the nature of single molecules in ambient conditions has remained challenging. Here, we demonstrate the hyperspectral TERS imaging of single brilliant cresyl blue (BCB) molecules, along with quantitative spectral 1 ar X iv :2 10 2. 02 40 8v 1 [ ph ys ic s. op tic s] 4 F eb 2 02 1 analyses, revealing their conformational heterogeneity in ambient conditions. Robust single… 

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