Probing molecular choreography through single-molecule biochemistry

Abstract

Single-molecule approaches are having a dramatic impact on views of how proteins work. The ability to observe molecular properties at the single-molecule level allows characterization of subpopulations and acquisition of detailed kinetic information that would otherwise be hidden in the averaging over an ensemble of molecules. In this Perspective, we… (More)
DOI: 10.1038/nsmb.3119

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