Probing metabolic states of differentiating stem cells using two-photon FLIM.

@article{Meleshina2016ProbingMS,
  title={Probing metabolic states of differentiating stem cells using two-photon FLIM.},
  author={Aleksandra V. Meleshina and Varvara V. Dudenkova and Marina V. Shirmanova and Vladislav I. Shcheslavskiy and Wolfgang Becker and Alena S. Bystrova and Elena I Cherkasova and Elena V Zagaynova},
  journal={Scientific reports},
  year={2016},
  volume={6},
  pages={21853}
}
The ability of stem cells to differentiate into specialized cell types presents a number of opportunities for regenerative medicine, stem cell therapy and developmental biology. Because traditional assessments of stem cells are destructive, time consuming, and logistically intensive, the use of a non-invasive, label-free approach to study of cell differentiation provides a powerful tool for rapid, high-content characterization of cell and tissue cultures. Here, we elucidate the metabolic… CONTINUE READING