Probing cell structure by controlling the mechanical environment with cell-substrate interactions.

@article{Cheng2009ProbingCS,
  title={Probing cell structure by controlling the mechanical environment with cell-substrate interactions.},
  author={Chao-Min Cheng and Robert L. Steward and Philip LeDuc},
  journal={Journal of biomechanics},
  year={2009},
  volume={42 2},
  pages={187-92}
}
Recent results demonstrate the exquisite sensitivity of cell morphology and structure to mechanical stimulation. Mechanical stimulation is often coupled with cell-substrate interactions that can, in turn, influence molecular response and determine cellular fates including apoptosis, proliferation, and differentiation. To understand these effects as they specifically relate to compressive mechanical stimulation and topographic control, we developed a microfabricated system to grow cells on… CONTINUE READING

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Structural phase coexistence under reversible thermal control

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