Probing Polytopic Membrane Protein-Substrate Interactions by Luminescence Resonance Energy Transfer.

Abstract

Integral membrane proteins play essential roles in all living systems; however, major technical hurdles challenge analyses of this class of proteins. Biophysical approaches that provide structural information to complement and leverage experimentally determined and computationally predicted structures are urgently needed. Herein we present the application… (More)
DOI: 10.1021/jacs.5b13426

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