Probing Alzheimer amyloid peptide aggregation using a cell-free fluorescent protein refolding method.

@article{Arslan2009ProbingAA,
  title={Probing Alzheimer amyloid peptide aggregation using a cell-free fluorescent protein refolding method.},
  author={Pharhad Eli Arslan and Avijit Chakrabartty},
  journal={Biochemistry and cell biology = Biochimie et biologie cellulaire},
  year={2009},
  volume={87 4},
  pages={631-9}
}
Fibrillation of the Alzheimer beta-amyloid peptide (Abeta) and (or) formation of toxic oligomers are key pathological events in Alzheimer's disease. Several strategies have been introduced to identify small molecule aggregation inhibitors, and based on these methods, a number of aggregation inhibitors have been identified. However, most of these methods use… CONTINUE READING