Probable zoonotic leprosy in the southern United States.

  title={Probable zoonotic leprosy in the southern United States.},
  author={Richard W. Truman and Pushpendra Singh and Rahul Sharma and Philippe Busso and Jacques Rougemont and A E Paniz-Mondolfi and A. Kapopoulou and Sylvain Brisse and David M. Scollard and Thomas Gillis and Stewart T Cole},
  journal={The New England journal of medicine},
  volume={364 17},
BACKGROUND In the southern region of the United States, such as in Louisiana and Texas, there are autochthonous cases of leprosy among native-born Americans with no history of foreign exposure. In the same region, as well as in Mexico, wild armadillos are infected with Mycobacterium leprae. METHODS Whole-genome resequencing of M. leprae from one wild armadillo and three U.S. patients with leprosy revealed that the infective strains were essentially identical. Comparative genomic analysis of… CONTINUE READING
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