Probability distribution of molecular evolutionary trees: A new method of phylogenetic inference

@article{Rannala1996ProbabilityDO,
  title={Probability distribution of molecular evolutionary trees: A new method of phylogenetic inference},
  author={Bruce Rannala and Ziheng Yang},
  journal={Journal of Molecular Evolution},
  year={1996},
  volume={43},
  pages={304-311}
}
A new method is presented for inferring evolutionary trees using nucleotide sequence data. The birth-death process is used as a model of speciation and extinction to specify the prior distribution of phylogenies and branching times. Nucleotide substitution is modeled by a continuous-time Markov process. Parameters of the branching model and the substitution model are estimated by maximum likelihood. The posterior probabilities of different phylogenies are calculated and the phylogeny with the… CONTINUE READING
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