Probabilistic modeling of the evolution of gene synteny within reconciled phylogenies

@inproceedings{Semeria2015ProbabilisticMO,
  title={Probabilistic modeling of the evolution of gene synteny within reconciled phylogenies},
  author={Magali Semeria and Eric Tannier and Laurent Gueguen},
  booktitle={BMC Bioinformatics},
  year={2015}
}
Most models of genome evolution concern either genetic sequences, gene content or gene order. They sometimes integrate two of the three levels, but rarely the three of them. Probabilistic models of gene order evolution usually have to assume constant gene content or adopt a presence/absence coding of gene neighborhoods which is blind to complex events modifying gene content. We propose a probabilistic evolutionary model for gene neighborhoods, allowing genes to be inserted, duplicated or lost… CONTINUE READING