Pro-inflammatory potential of ultrafine particles in mono- and co-cultures of primary cardiac cells.

@article{Totlandsdal2008ProinflammatoryPO,
  title={Pro-inflammatory potential of ultrafine particles in mono- and co-cultures of primary cardiac cells.},
  author={Annike Irene Totlandsdal and Tor Skomedal and Marit L{\aa}g and J Osnes and Magne Refsnes},
  journal={Toxicology},
  year={2008},
  volume={247 1},
  pages={23-32}
}
Inhalation of particulate air pollution has been associated with increased risks for cardiovascular mortality and morbidity, but the underlying mechanisms are still under discussion. One possible pathway may be that inhaled particles cross the air-blood barrier and interact directly with cardiac tissue. The aim of the present study was to examine the pro-inflammatory potential of particles in cardiac cells. Mono- and co-cultures of primary adult male Wistar (Han) rat cardiomyocytes (CMs) and… CONTINUE READING
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