Pro-inflammatory genetic profile and familiarity of acute myocardial infarction

  title={Pro-inflammatory genetic profile and familiarity of acute myocardial infarction},
  author={Manuela Ianni and Sergio Callegari and Antonio Rizzo and Paolo Pastori and Paolo Moruzzi and Domenico Corradi and Elisa Porcellini and Gianluca Campo and Roberto Ferrari and Marco Mario Ferrario and Stefania Bitonte and Ilaria Carbone and Federico Licastro},
  booktitle={Immunity & Ageing},
Acute myocardial infarction (AMI) is a multifactorial disease with a complex pathogenesis where lifestyle, individual genetic background and environmental risk factors are involved. Altered inflammatory responses are implicated in the pathogenesis of atherosclerosis and a premature AMI of parents is associated with an increased risk of the disease in their offspring (Offs). However, the genetic background of familiarity for AMI is still largely unknown. To understand which genes may predispose… CONTINUE READING
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