Pro-inflammatory cytokines and their effects in the dentate gyrus.

@article{Pickering2007ProinflammatoryCA,
  title={Pro-inflammatory cytokines and their effects in the dentate gyrus.},
  author={Mark Pickering and John J. O'Connor},
  journal={Progress in brain research},
  year={2007},
  volume={163},
  pages={
          339-54
        }
}
The older notion of a central nervous system existing in essential isolation from the immune system has changed dramatically in recent years as the body of evidence relating to the interactions between these two systems has grown. Here we address the role of a particular subset of immune modulatory molecules, the pro-inflammatory cytokines, in regulating neuronal function and viability in the dentate gyrus of the hippocampus. These inflammatory mediators are known to be elevated in many… CONTINUE READING
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