Pro-cognitive effects of 5-HT6 receptor antagonists in the social recognition procedure in rats: implication of the frontal cortex

@article{Loiseau2007ProcognitiveEO,
  title={Pro-cognitive effects of 5-HT6 receptor antagonists in the social recognition procedure in rats: implication of the frontal cortex},
  author={Florence Loiseau and Anne Dekeyne and Mark J Millan},
  journal={Psychopharmacology},
  year={2007},
  volume={196},
  pages={93-104}
}
Rationale5-HT6 receptor antagonists improve cognitive processes in rodents. However, their site(s) of action remains unexplored and their influence upon social memory has been little investigated.ObjectivesWe examined the influence of 5-HT6 receptor ligands upon social memory in rats by use of systemic or local administration into the frontal cortex (FCX), striatum, or nucleus basalis magnocellularis (NBM).Materials and methodsThe social recognition test is based upon the ability of an adult… Expand
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  • Medicine, Psychology
  • Neuropharmacology
  • 2008
TLDR
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