Pro-Resolving Lipid Mediators Improve Neuronal Survival and Increase Aβ42 Phagocytosis

@article{Zhu2015ProResolvingLM,
  title={Pro-Resolving Lipid Mediators Improve Neuronal Survival and Increase Aβ42 Phagocytosis},
  author={Mingqin Zhu and Xiuzhe Wang and Erik Hjorth and Romain Alexandre Colas and Lisa Schroeder and A. -Ch. Granholm and Charles N Serhan and Marianne Schultzberg},
  journal={Molecular Neurobiology},
  year={2015},
  volume={53},
  pages={2733-2749}
}
Inflammation in the brain is a prominent feature in Alzheimer’s disease (AD). Recent studies suggest that chronic inflammation can be a consequence of failure to resolve the inflammation. Resolution of inflammation is mediated by a family of lipid mediators (LMs), and the levels of these specialized pro-resolving mediators (SPMs) are reduced in the… CONTINUE READING