Prmt7 Deficiency Causes Reduced Skeletal Muscle Oxidative Metabolism and Age-Related Obesity.

@article{Jeong2016Prmt7DC,
  title={Prmt7 Deficiency Causes Reduced Skeletal Muscle Oxidative Metabolism and Age-Related Obesity.},
  author={Hyeon-Ju Jeong and Hye-Jin Lee and Tuan Anh Vuong and K S Choi and Dahee Choi and S K Koo and Sung Chun Cho and Hana Cho and J S Kang},
  journal={Diabetes},
  year={2016},
  volume={65 7},
  pages={1868-82}
}
Maintenance of skeletal muscle function is critical for metabolic health and the disruption of which exacerbates many chronic diseases such as obesity and diabetes. Skeletal muscle responds to exercise or metabolic demands by a fiber-type switch regulated by signaling-transcription networks that remains to be fully defined. Here, we report that protein arginine methyltransferase 7 (Prmt7) is a key regulator for skeletal muscle oxidative metabolism. Prmt7 is expressed at the highest levels in… CONTINUE READING
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