Prioritizing tests of epistasis through hierarchical representation of genomic redundancies

Abstract

Epistasis is defined as a statistical interaction between two or more genomic loci in terms of their association with a phenotype of interest. Epistatic loci that are identified using data from Genome-Wide Association Studies (GWAS) provide insights into the interplay among multiple genetic factors, with applications including assessment of susceptibility… (More)
DOI: 10.1093/nar/gkx505

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