Prior use of carbapenems may be a significant risk factor for extended-spectrum beta-lactamase-producing Escherichia coli or Klebsiella spp. in patients with bacteraemia.

@article{Martnez2006PriorUO,
  title={Prior use of carbapenems may be a significant risk factor for extended-spectrum beta-lactamase-producing Escherichia coli or Klebsiella spp. in patients with bacteraemia.},
  author={Jos{\'e} Antonio Mart{\'i}nez and Josefa Aguilar and Manel Almela and F. Ballenilla Marco and Alex Soriano and Fina L{\'o}pez and Valentina Balasso and Laura Pozo and Josep Maria Mensa},
  journal={The Journal of antimicrobial chemotherapy},
  year={2006},
  volume={58 5},
  pages={1082-5}
}
BACKGROUND The increasing prevalence of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae will probably trigger a rise in the use of carbapenems. The effect of these antibiotics on the risk of involvement of ESBL-producing organisms in serious infections is unclear. METHODS Retrospective analysis of 2172 episodes of healthcare-associated bacteraemia diagnosed during a 3 year period in a teaching hospital. Putative risk factors included demographics, co-morbidities, previous… CONTINUE READING