Prior stress attenuates the analgesic response but sensitizes the corticosterone and cortical dopamine responses to stress 10 days later

@article{Caggiula1989PriorSA,
  title={Prior stress attenuates the analgesic response but sensitizes the corticosterone and cortical dopamine responses to stress 10 days later},
  author={Anthony R. Caggiula and Seymour M. Antelman and Edward A. Aul and Steven Knopf and D. A. Edwards},
  journal={Psychopharmacology},
  year={1989},
  volume={99},
  pages={233-237}
}
This study demonstrates that pre-exposure to stress influences subsequent effects of stress on pain sensitivity (stress-induced analgesia) and on plasma corticosterone and brain catecholamine activity. Animals exposed to a 30 min shock session (S1=8, 5.0 s shocks) 10 days earlier showed a significant attenuation of shock-induced analgesia, as measured by increased latency of tail withdrawal from a hot water bath immediately after a 40 s, 1.6 mA footshock (S2). Animals exposed to shock 10 days… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 23 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 35 REFERENCES

Opposite effects of chronic iraipramine treatment of brain and urine MHPG levels in the rat

  • H Seyle
  • Biol Psychiatry
  • 1986

Stress, cancer and the mind. In: Day SB (ed) Cancer, stress and death

  • H Seyle
  • 1986
1 Excerpt

Similar Papers

Loading similar papers…