Prior pallidotomy reduces and modifies neuronal activity in the subthalamic nucleus of Parkinson's disease patients.

@article{Zaidel2008PriorPR,
  title={Prior pallidotomy reduces and modifies neuronal activity in the subthalamic nucleus of Parkinson's disease patients.},
  author={Adam Zaidel and Anan Moran and G Marjan and Hagai Bergman and Zvi Israel},
  journal={The European journal of neuroscience},
  year={2008},
  volume={27 2},
  pages={483-91}
}
Parkinson's disease (PD) patients with prior radio-frequency lesions in the internal segment of the globus pallidus (GPi, pallidotomy), whose symptoms have deteriorated, may be candidates for further invasive treatment such as subthalamic deep brain stimulation (STN DBS). Six patients with prior pallidotomy (five unilaterally; one bilaterally) underwent bilateral STN DBS. The microelectrode recordings (MERs, used intraoperatively for STN verification), ipsilateral and contralateral to… CONTINUE READING

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Prior pallidotomy reduces and modifies neuronal activity in the subthalamic nucleus

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