Prior hypoglycemia enhances glucose responsiveness in some ventromedial hypothalamic glucosensing neurons.

@article{Kang2008PriorHE,
  title={Prior hypoglycemia enhances glucose responsiveness in some ventromedial hypothalamic glucosensing neurons.},
  author={Ling Kang and Nicole M. Sanders and Ambrose A. Dunn-Meynell and Larry D Gaspers and Vanessa H. Routh and A. P. Thomas and Barry E. Levin},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2008},
  volume={294 3},
  pages={R784-92}
}
Antecedent insulin-induced hypoglycemia (IIH) reduces adrenomedullary responses (AMR) to subsequent bouts of hypoglycemia. The ventromedial hypothalamus [VMH: arcuate (ARC) + ventromedial nuclei] contains glucosensing neurons, which are thought to be mediators of these AMR. Since type 1 diabetes mellitus often begins in childhood, we used juvenile (4- to 5-wk-old) rats to demonstrate that a single bout of IIH (5 U/kg sc) reduced plasma glucose by 24% and peak epinephrine by 59% 1 day later… CONTINUE READING

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Prior hypoglycemia enhances glucose responsiveness in some ventromedial hypothalamic glucosensing neurons .
Prior hypoglycemia enhances glucose responsiveness in some ventromedial hypothalamic glucosensing neurons .
HypoglycemiaMay be treated byGlucose
Prior hypoglycemia enhances glucose responsiveness in some ventromedial hypothalamic glucosensing neurons .
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