Prior experience, antioxidants, and mitochondrial cofactors improve cognitive function in aged beagles.
@article{IkedaDouglas2004PriorEA, title={Prior experience, antioxidants, and mitochondrial cofactors improve cognitive function in aged beagles.}, author={Candace J. Ikeda-Douglas and Steven Curtis Zicker and Jimena Estrada and Dennis E. Jewell and Norton W. Milgram}, journal={Veterinary therapeutics : research in applied veterinary medicine}, year={2004}, volume={5 1}, pages={ 5-16 } }
Results of this study support the free-radical theory of aging and demonstrated that providing higher levels of vitamin E in food resulted in higher serum vitamin E concentrations and improved performance on landmark-discrimination tasks in aged dogs. Factors other than vitamin E also contributed to the response but remain undefined.
29 Citations
Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine.
- BiologyThe Canadian veterinary journal = La revue veterinaire canadienne
- 2008
It is suggested that the nutraceutical supplement can improve memory in aged dogs and the effect was long lasting.
Short-term supplementation with acetyl-l-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles
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Nutraceuticals for Cognitive Dysfunction
- BiologyNutraceuticals in Veterinary Medicine
- 2019
Various nutraceuticals and substances that have potential to improve cognition and memory in senior dogs and cats are described.
Learning ability in aged beagle dogs is preserved by behavioral enrichment and dietary fortification : a two-year longitudinal study
- Psychology, Biology
- 2004
It is suggested that behavioral enrichment or dietary fortification with antioxidants over a long-duration can slow age-dependent cognitive decline, and that the two treatments together are more effective than either alone in older dogs.
Learning ability in aged beagle dogs is preserved by behavioral enrichment and dietary fortification: a two-year longitudinal study
- Psychology, BiologyNeurobiology of Aging
- 2005
Therapeutic agents for the treatment of cognitive dysfunction syndrome in senior dogs
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- 2005
Nutrition and behavior in senior dogs.
- MedicineTopics in companion animal medicine
- 2011
Dietary treatment of CDS has been based on the use of antioxidants and mitochondrial cofactors, and recent work has shown that long-term supplementation with medium-chain triglycerides can improve cognitive function in aged dogs.
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Therapeutic options for cognitive decline in senior pets.
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The theory, evidence of efficacy, and potential neuroprotective effects of products used to treat cognitive dysfunction, including drugs, nutritional supplements, and diets for senior pets are described.
Protective effect of honey on learning and memory impairment, depression and neurodegeneration induced by chronic unpredictable mild stress
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- 2020
Honey diminished learning and memory deficits and depression in chronic stress conditions and reduced the malondialdehyde level in treated animals.
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