Prior DNA immunization enhances immune response to dominant and subdominant viral epitopes induced by a fowlpox-based SIVmac vaccine in long-term slow-progressor macaques infected with SIVmac251.

Abstract

A therapeutic vaccine for individuals infected with HIV-1 and treated with antiretroviral therapy (ART) should be able to replenish virus-specific CD4+ T-cells and broaden the virus-specific CD8+ T-cell response in order to maintain CD8+ T-cell function and minimize viral immune escape after ART cessation. Because a combination of DNA and recombinant… (More)

Topics

Cite this paper

@article{Radaelli2003PriorDI, title={Prior DNA immunization enhances immune response to dominant and subdominant viral epitopes induced by a fowlpox-based SIVmac vaccine in long-term slow-progressor macaques infected with SIVmac251.}, author={Antonia Radaelli and J{\'a}nos Nacsa and Wen Po Tsai and Yvette Y Edghill-Smith and Carlo Zanotto and Veronica Elli and David J Venzon and Elżbieta Anna Tryniszewska and Phil Markham and Gail P. Mazzara and Dennis L. Panicali and Carlo De Giuli Morghen and Genoveffa Franchini}, journal={Virology}, year={2003}, volume={312 1}, pages={181-95} }