Prions and the oral cavity.

  title={Prions and the oral cavity.},
  author={Andrew P. Smith and Jeremy Bagg and James W Ironside and Robert G. Will and Crispian Scully},
  journal={Journal of dental research},
  volume={82 10},
Prion diseases have recently emerged as a significant challenge to health-care workers, including those involved in dentistry. Abnormal prion proteins are resistant to complete inactivation by conventional sterilization techniques. In the last decade, a new form of prion disease emerged in the UK, termed "variant CJD", thought to be acquired by consumption of bovine spongiform encephalopathy-contaminated food products. At present, CJD is an invariably fatal disease with no immediate prospect of… CONTINUE READING