Prion protein polymerisation triggered by manganese-generated prion protein seeds.

@article{Hesketh2012PrionPP,
  title={Prion protein polymerisation triggered by manganese-generated prion protein seeds.},
  author={Shirley Hesketh and Andrew R. Thompsett and David R Brown},
  journal={Journal of neurochemistry},
  year={2012},
  volume={120 1},
  pages={177-89}
}
Prion diseases are neurodegenerative diseases that can be transmitted between individuals. The exact cause of these diseases remains unknown. However, one of the key events associates with the disease is the aggregation of a cellular protein, the prion protein. The mechanism of this is still unclear. However, it is likely that the aggregation is trigged by… CONTINUE READING