Prion protein is secreted in soluble forms in the epididymal fluid and proteolytically processed and transported in seminal plasma.

@article{Gatti2002PrionPI,
  title={Prion protein is secreted in soluble forms in the epididymal fluid and proteolytically processed and transported in seminal plasma.},
  author={J. L. Gatti and Sonia M{\'e}tayer and Mohammed Moudjou and Olivier Andr{\'e}oletti and Fr{\'e}d{\'e}ric Lantier and Jean-Louis Dacheux and Pierre Sarradin},
  journal={Biology of reproduction},
  year={2002},
  volume={67 2},
  pages={
          393-400
        }
}
The presence of prion protein in sperm and fluids collected from different parts of the ram genital tract was investigated by immunoblotting with monoclonal antibodies. A slightly immunoreactive 25- to 30-kDa protein was recognized on Western blots of testicular and epididymal sperm extracts. Immunoreactivity increased on ejaculated sperm extracts and 2 other bands at 35 and 43 kDa also reacted. Seminal plasma showed several immunoreactive bands, the main bands being detected at 43 and 35 kDa… CONTINUE READING

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