Prion protein degradation by lichens of the genus Cladonia

@article{Bennett2012PrionPD,
  title={Prion protein degradation by lichens of the genus Cladonia},
  author={James P. Bennett and Cynthia M. Rodriguez and Christopher J. Johnson},
  journal={The Lichenologist},
  year={2012},
  volume={44},
  pages={523 - 531}
}
Abstract It has recently been discovered that lichens contain a serine protease capable of degrading the pathogenic prion protein, the etiological agent of prion diseases such as sheep scrapie and cervid chronic wasting disease. Limited methods are available to degrade or inactivate prion disease agents, especially in the environment, and lichens or their serine protease could prove important for management of these diseases. Scant information is available regarding the presence or absence of… Expand
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References

SHOWING 1-10 OF 24 REFERENCES
Degradation of the Disease-Associated Prion Protein by a Serine Protease from Lichens
TLDR
These findings indicate that these lichen extracts efficiently degrade PrPTSE and suggest that some lichens could have potential to inactivate TSE infectivity on the landscape or be a source for agents to degrade prions. Expand
Lichens: unexpected anti-prion agents?
TLDR
It is speculated that lichens could have the potential to degrade prions when they are shed from infected animals onto lichens or into environments where lichens are abundant, and the effect of dietary lichens on prion disease transmission should be considered. Expand
Fate of prions in soil: a review.
TLDR
An improved understanding of the processes affecting the mobility, persistence, and bioaviailability of prions in soil is needed for the management of TSE-contaminated environments. Expand
The Expanding Universe of Prion Diseases
TLDR
The origins of emergent prion diseases cannot always be laid at the door of humankind, and the continued appearance of new outbreaks in the form of “sporadic” disease may be an inevitable outcome in a situation where the replicating pathogen is host-encoded. Expand
A prion disease of cervids: chronic wasting disease.
Chronic wasting disease (CWD) is a prion disease of deer, elk, and moose, initially recognized in Colorado mule deer. The discovery of CWD beyond the borders of Colorado and Wyoming, in Canada and asExpand
Secreted arginases from phylogenetically farrelated lichen species act as cross-recognition factors for two different algal cells.
TLDR
Data demonstrate ligand-dependent retention of the fungal lectin on the algal cell surface and this is consistent with a model of recognition of compatible algae, through which algal cells would form a lichen with a lectin-secreting fungus only when these cells contain the specific ligand for the lectin in their cell walls. Expand
The Wisdom of Fools: new molecular and morphological insights into the North American apodetiate species of Cladonia
TLDR
Molecular evidence gives an equivocal answer to the question of whether C. petrophila is a distinct monophyletic entity or if C. apodocarpa is nested within it, and a morphologically and ecologically distinct new taxon is described as C. stipitata. Expand
Phylogeny of the Genus Cladonia s.lat. (Cladoniaceae, Ascomycetes) Inferred from Molecular, Morphological, and Chemical Data
TLDR
Phylogenetic relationships within the genus Cladonia, including Cladina, were reconstructed based upon simultaneous analyses of DNA sequences and morphological and chemical data, and a new provisional classification for the genus is proposed. Expand
Inactivation of transmissible degenerative encephalopathy agents: A review.
  • D. Taylor
  • Biology, Medicine
  • Veterinary journal
  • 2000
TLDR
The infectivity levels in histologically-fixed tissue can be reduced substantially by treatment with concentrated formic acid without adversely affecting the microscopic quality of the tissue. Expand
The Macrolichens of New England
TLDR
Examining material in the field, from their own collections, and from other herbaria, James and Patricia Hinds verified 425 species of the lichenized fungi that occur in New England, and accepted an additional 36 species from publications or from correspondence with other lichenologists. Expand
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